Dr.Manjunatha H.
M.Sc.Ph.D
Assistant Professor
Department of Biotechnology
manjunatha75@gmail.com

 
           

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  • Area Of Research

               
    SL # Topic
    1 Biochemistry and Systems Biology


    Journals Publications

               
    SL # Authors Title Impact Factor Publisher Year
    1 Thriveni V, Manjunatha H, Santhosh KH Hepatoprotective effect of curcumin and capsaicin against Lipopolysaccharide induced liver damage in mice 0 Pharmacognocy 2017
    2 Sharath BS, Shivananda Kandagalla, Pavan Gollapalli, Bharath BR, Thriveni vasanthkumar, Manjunatha H Topology of protein-protein interaction network and edge reduction co-efficiency in VEGF signaling of breast cancer 0 Springer 2017
    3 Basavapattana Rudresh Bharath, Thriveni Vasanthkumar, Hanumanthappa Manjunatha, Chakravarthi Bharath Interaction of curcumin and capsaicin with LPS induced TRAF6 expression in peripheral blood mononuclear cells 1.277 Springer 2017
    4 TRIVENI VASANTH KUMAR, MANJUNATHA H.,RAJESH KP ANTI-INFLAMMATORY ACTIVITY OF CURCUMIN AND CAPSAICI N AUGMENTED IN COMBINATION 0 International Journal of Pharmacy and Pharmaceutical Sciences 2017
    5 Manjunatha Bhat, G. K. Nagaraja, Reshma Kayarmar, S. V. Raghavendra, K. P. Rajesh, H. Manjunatha Synthesis, characterization and pharmacological evaluation of some new 1,3,4-oxadiazole derivatives bearing 3-chloro-2-fluoro phenyl moiety 1.833 Springer 2016
    6 Lokeshwari D, Krishna Kumar NK, Manjunatha H. Multiple Mutations on the Second Acetylcholinesterase Gene Associated With Dimethoate Resistance in the Melon Aphid, Aphis gossypii (Hemiptera: Aphididae). 1.609 Oxford academic 2016
    7 D. Lokeshwari , N. K. Krishna Kumar , and H. Manjunatha Comparative Biological and Molecular studies on host-adapted populations of the melon aphid, Aphis gossypii (Hemiptera: Aphididae) in India 4.589 Oxford University Press 2016
    8 D. Lokeshwari N. K. Krishna Kumar H. Manjunatha Molecular Diversity of the Aphis gossypii (Hemiptera: Aphididae): A Potential Vector of Potyviruses (Potyviridae) 1.14 Annals of the Entomological Society of America 2015
    9 Gollapalli, Pavan; Hanumanthappa, Manjunatha; Pattar, Sharath Cluster Analysis of Protein-protein interaction network of Mycobacterium tuberculosis during Host infection. 0.97 Advances in Bioresearch 2015
    10 Reshma Kayarmar, G.K.Nagaraja, PrashanthaNaik, H.Manjunatha, B.C.Revanasiddappa, T.Arulmoli Synthesis and characterization of novel imidazoquinoline based 2-azetidinones as potent antimicrobial and anticancer agents 2.523 Elsevier 2014
    11 Sunil Joshi, D. Lokeshwari, N. K. Krishna Kumar, H. Manjunatha, Abraham Verghese, K. Jalali Wahlgreniella nervata (Hemiptera: Aphididae), a new pest of rose in India 1.052 Florida Entomologist 2014
    12 D. Lokeshwari, M. Hayat, N. K. Krishna Kumar, H. Manjunatha, R. Venugopalan First occurrence of the aphid parasitoid, Aphelinus basilicus (Hymenoptera: Aphelinidae), on Aphis gossypii (Hemiptera: Aphididae) color forms in India. 1.052 Florida Entomologist 2014
    13 Lokeshwar, NK Krishna Kumar, Manjunatha H Effect of Aphis odinae (Hemiptera: Aphididae) Infestation on Sugars and Amino Acid Content in mango 0.365 African Entomology 2014
    14 D. Lokeshwari, N. K. Krishna Kumar, H. Manjunatha Color polymorphism does not affect species diagnosis of the melon aphid, Aphis gossypii (Hemiptera: Aphididae) 1.052 Florida Entomologist 2014
    15 Govindappa N, Hanumanthappa M, Venkatarangaiah K, Periyasamy S, Sreenivas S, Soni R, Sastry K. A new signal sequence for recombinant protein secretion in Pichia pastoris. 1.685 Journal of Microbiology and Biotechnolog 2014
    16 B R Bharath, B Sujata, K P Rajesh, D M Chetan, H Manjunatha Comprehensive Analysis of Homologous Proteins for Specific Drug Design 1.473 Technology and Arts Research Journal 2014
    17 K P Rajesh, H manjunatha, B R Bharath Simulated Screening of flavonoids as probable anti-Helicobacter pylori drug 1.402 Springer 2013
    18 K.P.Rajesha, Manjunatha H, V.Krishna, B.E.Kumara Swamy Potential in vitro antioxidant and protective effects of Mesua ferrea Linn. bark extracts on induced oxidative damage 2.837 Elsevier 2013
    19 Rajesh Kashi Prakash Gupta, Pradeepa, Manjunatha Hanumanthappa In vitro Antioxidant and H+, K+ -ATPase inhibition activities of Acalypha wilkesiana foliage extract 0.855 J Pharm. Bioallied Sci. 2013
    20 BR Bharath, H Manjunatha Flux Balance Analysis Based Model for the Identification of Potent Drug Target: A Novel Strategy. 1.473 Sci. technol. arts Res. J., 2013
    21 Govindappa N, Hanumanthappa M, Venkatarangaiah K, Kanojia K, Venkatesan K, Chatterjee A, Kusumanchi PMT1 gene plays a major role in O-mannosylation of insulin precursor in Pichia pastoris. 1.695 Elsevier 2013
    22 Bharath BR, Manjunatha H, Santosh Kumar HS and Bharath K Non Linear Flux Assessment Model for Endotoxin Neutralizing Pathways 1.59 ComputSciSystBiol 2013
    23 Yadav D Bodke, Aruna Sindhe M, Rajesh K. Gupta, Manjunatha H Antioxidant and anthelmintic activity of Terminalia arjuna Roxb. stem bark extracts. 1.062 Asian J of Pharma & Clin Res 2013
    24 H G Vidyavati, H. Manjunatha, J Hemavathy, K. Srinivasan Hypolipidemic and antioxidant efficacy of dehydrated onion in experimental rats 2.203 Springer 2012
    25 B K Sarojini, M Vidyagayatri, C G Darshanraj, B R Bharath, H Manjunatha. DPPH Scavenging Assay of Novel 1,3-disubstituted-1H-pyrazol-5-ols and their in silico Studies on Some Proteins Involved in Alzheimers Disease Signaling Cascade 0.77 Bentham science 2012
    26 Satyendra,Vishnumurthy, Vagdevi , P Rajesh,H Manjunatha, A Shruthi In vitro antimicrobial and molecular docking of dichloro substituted benzoxazole derivatives 1.402 Springer 2012
    27 Darshan Raj, B K Sarojini, M K Ramakrishna, S R Ramesh, H Manjunatha In vivo peritoneal anti-angiogenesis and in vitro anti-proliferative properties of some bischalcone derivatives 1.402 Springer 2012
    28 S M Vidya, V Krishna, B K Manjunatha, Rajesh, B R Bharath, H Manjunatha Antibacterial and molecular docking studies of entagenic acid, a bioactive principle from seed kernel of Entada pursaetha 1.402 Springer 2012
    29 S M Vidya, V Krishna, B K Manjunatha, Rajesh, B R Bharath, H Manjunatha Wound healing phytoconstituent from seed kernel of Entada pursaetha DC and their molecular docking studies with glycogen-synthase-kinase-3-β 1.402 Springer 2012
    30 Satyendra RV, Vishnumurthy KA, Vagdevi HM, Rajesh KP, Manjunatha H, Shruthi A. Synthesis, in vitro antioxidant, anthelmintic and molecular docking studies of novel dichloro substituted benzoxazole-triazolo-thione derivatives 3.447 Elsevier 2011
    31 Y.S.Ravikumar, K.M.Mahadevan, H.Manjunatha, N.D.Satyanarayana Antiproliferative,apoptoticandantimutagenicactivityofisolated compounds from Polyalthiacerasoides seeds 3.126 Elsevier 2010
    32 Sarojini BK, Krishna BG, Darshanraj CG, Bharath BR, Manjunatha H. Synthesis, characterization, in vitro and molecular docking studies of new 2,5-dichloro thienyl substituted thiazole derivatives for antimicrobial properties 3.447 Elsevier 2010
    33 Gouthamchandra K, Mahmood R, Manjunatha H. Free radical scavenging, Antioxidant enzymes and wound healing activity of leaves extract from clerodendrun infortunatum L 2.084 Elsevier 2010
    34 Habbu PV, Mahadevan KM, Shastry RA, Manjunatha H. Antimicrobial activity of flavanoid sulphates and other fractions of Argyreia speciosa (Burm.f) Boj. 0.835 Indian Journal of Experimental Biology. 2009
    35 D.Suresh,H Manjunatha, Krishnapura Srinivasan Effect of heat processing of spices - turmeric, red pepper and black pepper on the concentration of their bioactive principles. 1.985 Elsevier 2007
    36 Manjunatha H, Srinivasan K Hypolipidemic and antioxidant effect of curcumin and capsaicin in high fat fed rats 1.77 NRC Research press 2007
    37 Manjunatha H, Srinivasan K Hypocholesterolemic and antioxidant effect of curcumin and capsaicin in induced hyper-cholesterolemic rats 1.854 Springer 2007
    38 Kempaiah RK, Manjunatha H, Srinivasan K Protective effect of dietary capsaicin on induced oxidation of low-density lipoprotein in rats. 2.393 Springer 2006
    39 Manjunatha H, Srinivasan K Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats. 2.393 FEBS 2005

    Books

    SL # Authors Title Publisher Year
                           

    Book Chapters

    SL # Authors Title Publisher Year

    Conferences

    SL # Authors Title Organizer Year
    1 Manjunatha .H Identification of putative drug target using ligand based protein network approach in TGF-BETA induced epithelial to mesenchymal transition (EMT) A National level student symposium organized by dept. of BTE NMAMIT, Nitte, Karkala 2017
    2 Manjunatha .H In silico ADMET and multiligand docking of Hsp90 with herbal compounds, Curcumin and epigallocatechin. International conference – Importance of herbal medicine in area in the era of globalization- A live 2016
    3 Manjunatha .H Evaluation of analgesic activity of silver nanoparticle using Brugmansia suaveolens (Bercht, and Pres). 28th International symposium on “Understanding the molecules of life in the era of new biology” held 2016
    4 Manjunatha .H Homology modeling and docking of Hsp90 with epigallocatechin. Page No. 63 National seminar on “Frontier research in diversity and taxonomy of medicinal plants.” held at Biolo 2016
    5 Manjunatha .H In silico study of curcumin and its derivative on CREB binding protein. Page No. 55 National seminar on “Frontier research in diversity and taxonomy of medicinal plants.” held at Biolo 2016
    6 Manjunatha .H Cryptostegia grandiflora (R.Br); In vivo detection of neurotransmitter using cyclic voltammetry Page No. 57 National seminar on “Frontier research in diversity and taxonomy of medicinal plants.” held at Biolo 2016
    7 Manjunatha .H In silico and in vitro lipoxygenase inhibitory activity of beta-stosterol isolated from Mesua Ferrea Linn. Page No. 44 National seminar on “Frontier research in diversity and taxonomy of medicinal plants.” held at Biolo 2016
    8 Manjunatha .H Potential in vitro antioxidant and protective effects of dietary curcumin and capsaicin on induced oxidative damage International conference on Applications of Natural products and Opportunities ahead (ICAN-2016) hel 2016
    9 Manjunatha .H Effects of curcumin and capsaicin on expression of proinflammatory cytokine TNF-α in human peripheral blood mononuclear cells (PBMCs) International conference on science and technology: future Challenges and solutions (STFCS-2016) hel 2016
    10 Manjunatha .H Effects of dietary Curcumin and Capsaicin on proinflammatory cytokines IL-6 and TNF-α in Peripheral blood mononuclear cells (PBMCs) of human subjects. Page No. 61 National seminar on “Frontier research in diversity and taxonomy of medicinal plants.” held at Biolo 2016
    11 Manjunatha .H Evaluation of in vivo anti-inflammatory activity of stem bark extract of Mesua ferrea linn in rats. International, 7, 8, 9th March 2016. ‘Environment and Ecology’ Bharathiar University, Coimbatore 2016
    12 Manjunatha .H Isolation, Identification and molecular docking studies of compound from Cryptostegia grandiflora (R.Br). Page No. 67 International (8th -9th June 2012) on Exploration of biotechnology by student scholar and research-2 2016
    13 Manjunatha .H Binding interaction of curcumin and capsaicin with TRAF6 protein isolated from monocytes using cyclic voltammetry technique. CPP-38 International (26th to 28th Feb 2015) “Bioactive chemicals for reproduction and human health” Life 2015
    14 Manjunatha .H Evaluation if in vitro anti-inflammatory activity of Mesuae ferrea Linn. CPP - 37 International (26 to 28th Feb 2015) “Bioactive chemicals for reproduction and human health” Life s 2015
    15 Manjunatha .H Systems biology approach to analyze LPS induced protein int5eraction network substantiated by in vitro studies. Page No. 69 National conference on bench to bedside during 27 to 28th 2013, Dept. of Bitechnology, Sahyadri Scie 2013
    16 Manjunatha .H Non-linear metabolic flux assessment of endotoxin clearing TLR4 pathway. Page No. 109 International (19 to 22nd February 2012) International conference on Molecular Medicine “molmed -201 2012
    17 Manjunatha .H In vitro antioxidant arbitrated protective effect on oxidative damage in erythrocytes by Mesua ferrea Linn. Page No. 190 International (19 to 22nd February 2012) Conference on Molecular Medicine “molmed -2012 Center for B 2012
    18 Manjunatha .H Studies on the in vivo antidiabetic potential and in silico docking analysis of Quercetin. Page No. 117 International (19 to 22nd February 2012) International conference on Molecular Medicine “molmed -201 2012
    19 Manjunatha .H Virtual screening of phytochemical constituent molecules for anti- Helicobacter pylori activity. Page No. 41 State level (8 & 9th April, 2011) conference on Mesmerizing fields of Biotechnolgy, Dept of PG studi 2011
    20 Manjunatha .H Wound healing phytoconstituents from the seed kernel of Entada pursaetha DC. and there molecular docking studies with GSK 3-β. Page No. 29 National (10 & 11th of Sep 2011) conference on “Herbal Medicines in the era of Globalization, Dept. 2011
    21 Manjunatha .H Annotation of hypothetical genes and MD simulation, NMA of a protein containing PE domain. Page No. 28 National (26 to 27th, March 2011) on social relevance of chemical sciences Dept. of Chemistry, Kuvem 2011
    22 Manjunatha .H Wound healing potential of methanol leaf extract of Brugmansia suaveolens in rats. Page No. 50 State level (8 & 9th April, 2011) conference on Mesmerizing fields of Biotechnolgy, Dept of PG studi 2011
    23 Manjunatha .H In vitro antioxidant potential of methanol extract of Cryptostagia grandiflora. Page No. 51 National (21st Sept 2011) Dissecting the complexities of plant biotechnology in the post genomic era 2011
    24 Manjunatha .H Antibacterial and Molecular docking studies of entagenic acid, a bioactive principle from seed kernel of Entada pursaetha DC. Page No. 23 National (26 &27th, March 2011) Conference on “Social Relevance of Chemical Sciences (SRCS-2011) Dep 2011
    25 Manjunatha .H Dynamical properties and Conformational flexibility of Mycobacterium tuberculosis HSP 60.2: MD simulations and Normal mode analysis approach”. Page No. 174 International (18-21st Jan – 2010) The Eighth Asia Pacific Bioinformatics Conference, Indian Institu 2010
    26 Manjunatha .H Comparative structure analysis of homologous proteins for specific drug design. Page No. S61 4th International (17 to 21st Feb, 2010) symposium on current trends in drug discovery research 2010
    27 Manjunatha .H Hepatocurative profile of Sachytarpheta indica, a phytomedicine. Page No. 134 International herbal conference on herbal medicine (Feb, 26-28th, 2009) Association of pharmaceuti 2009
    28 Manjunatha .H Antioxidant and anti-inflammatory activity of capsaicin. Page 157 International (July 25-27th, 2009) Symposium on Environmental Pollution, Ecology, Health and Human H 2009
    29 Manjunatha .H Diosogenin: A Potent Anti-inflammatory molecule. Page 157 International (July 25-27th, 2009) Symposium on Environmental Pollution, Ecology, Health and Human H 2009
    30 Manjunatha .H Hepatoprotective role of Eugenia jambolana Lam, Bark on ferrous sulphate induced hepatic damage in rats. Page No. 134 International herbal conference on herbal medicine (Feb, 26-28th, 2009) Association of pharmaceuti 2009
    31 Ravikumar YS, Mahadevan KM, Kumaraswamy MN, Vaidya VP, Manjunatha H, Kumar V, Satyanarayana ND Antioxidant, cytotoxic and genotoxic evaluation of alcoholic extract of Polyalthia cerasoides (Roxb.) Bedd. Elsevier 2008
    32 Manjunatha .H Protective effect of dietary capsaicin on induced oxidation of low density lipoprotein in rats 73rd National (Nov 21 to 24th, 2004) annual meeting of SBC (I). G.B. Pant university of Agriculture 2004
               

    Articles

    SL # Authors Title Publisher Year
  • Research Projects

               
    SL # Title Funding Agency Co-Investigator Amount status
    1 Evaluation of Antioxidant and Anti-gastric ulcer property of Mesua ferrea Linn. DBT, New Delhi Prof. Krishna V. 1151000 Completed
    2 Molecular mechanisms of combined inhibitory effect of dietary curcumin and capsaicin on endotoxin induced inflammation DST-SERB, New Delhi Nil 1200000 ongoing
    3 Studies on the endotoxin neutralizing protein interaction network with anti-inflammatory UGC, New Delhi Dr. Kumara Swamy B E 873500 Completed
  • Awards

               
    SL # Award Name Award For Organization Year
    1 Bir Singh Aasi Memorial award 2016 Best publication award Society for advancement of human and nature, India 2016
    2 Certificate of excellence in Reviewing Reviewer Science Domain International, New Castle USA 2016
    3 Rapid Grant for Young Investigator (RGYI award) Research DBT 2010
    4 CSIR-UGC NET CSIR-JRF NET CSIR 1999
  • Patents

               
    SL # Investigator Name Title Year
  • Research Scholars

               
    SL # Name Title Research Type
    1 Sharath B S 978569742060 Drug target identification through dynamic of protein interaction network analysis using VEGF induced monocytes Ph.D.
    2 Thriveni V 276786848037 Studies on anti-inflammatory potency of dietary curcumin and capsaicin Ph.D.
    3 shivananda kandagalla 525257469197 Identification of drug target using protein interaction network of TGF-beta induced epithelial to mesenchymal transition[EMT] Ph.D.
    4 Umme hani 423229959538 Studies on the effect of epigallocatechin on the Hsp90 mediated inflammation Ph.D.
    5 Prathima R 499063059878 Studies on the anti-inflammatory activities of extract from mesus ferres linn. Ph.D.
  • Research Alumni

               
    SL # Name Title of Thesis Research Type Year Address Email Id
    1 DEEPA R STUDIES ON THE DEVELOPMENT OF BIOSENSOR FOR THE DETERMINATION OF DOPAMINE USING THE PHYTOCONSTITUENTS OF PTEROCARPUS MARSUPIUM ROXB. Ph.D. 2015 Shankaraghatta, shimoga, karnataka, India 176deeps@gmail.com
    2 G. NAGARAJA ROLE OF PROTEIN MANNOSYLTRANSFERASE IN O-GLYCOSYLATION OF INSULIN PRECURSOR EXPRESSED IN PICHIA PASTORIS Ph.D. 2014 CHIEF SCIENTIFIC MANAGER, BIOCON LIMITED, BANGALURE nagaraj.govindappa@biocon.com
    3 SANTHOSH K.H PHYTOCHEMICAL SCREENING FOR ACTIVE CONSTITUENTS AND EVALUATION OF PHARMACOLOGICAL PROPERTIES OF CRYPTOSTEGIA GRANDIFLORA Ph.D. 2014 Department of Biotechnology, Jnana sahyadri, Kuvempu University, Shankaraghtaa, shimoga santhoshbio4@gmail.com
    4 RAJESH KP EVALUATION OF ANTI-GASTRIC ULCER PROPERTY OF MESUS FERREA LINN. Ph.D. 2014 Biocon research centre, Biocon, Bangalore, Karnataka, India. rajeshgupth@gmail.com